Pain and Addiction CME Quiz Name(Required) First Last Credentials Email(Required) Which therapies can be used on closed brain tumors? Mistletoe, H2O2 Nutrients only DMSO, Nutrients NAD, B6 What is true about fat soluble vitamins? The fat soluble vitamins can accumulate if given in too high dose over time and may result in toxicity The fat-soluble vitamins, including A, D, E, K and biotin are available in “water soluble” forms as stable emulsions The fat soluble vitamins are relatively non-toxic as they do not accumulate in the body DO NOT give to patients with liver disease or liver cancer Vitamin D Excessive Vitamin D leads to serum hypocalcemia Has a contraindication in primary hypoparathyroid disease Deficiencies can allow for more sensitivities to aflatoxin Has no correlation to inflammation and infection Which statement is true? High Dose Vitamin C produces H2O2 intracellularly and has the potential for cell damage by this mechanism. H2O2 infusion gets intracellularly when using DMSO to drive it into the cell. Providing the mechanism for H2O2 mediated cell damage. High Dose Vitamin C produces H2O2 extracellularly and in the plasma. Ozone is the only oxidative therapy that can produce H2O2 intracellularly What is the most common preservative used with IV Curcumin products? Sodium Bicarb- check for patient intolerances Sodium Hydroxide- check for patient intolerances Benzyl Alcohol- check for patient intolerances Potassium Sorbate- check for patient intolerances Which statement is FALSE about IV Curcumin? Safe at doses used in common protocols Start low and titrate up to dose needed IV form is a lipid The water soluble form is safe and comfortable for IV administration. Which B Vitamin is the lease likely to flare up a chronic disease patient? Thiamin Pyridoxine Dexpanthenol Methyl cobalamin Ozone’s mechanism of regeneration is all EXCEPT: Improved oxygenation Increased Lipid Oxides (LOP) and cytokine signals Sterilization of the site Upregulation of antioxidant pathways Which nutrient initiates the electron transport chain? Iron CoQ10 NAD Copper NAD is the rate limiting factor in the synthesis of which neurotransmitter? Serotonin Dopamine Cortisol Insulin NAD acts as an anti-aging mechanism by stimulating SIRTs (Sirtuins) PARPs (Poly ADP-ribose polymerase) CD38 ATP NAD can be depleted by Riboflavin, Drugs, Pesticides Oral NAD supplementation Alcohol, Hydrogenated fats, Magnesium, Iron, CoQ10 Your next patient arrives for their IV nutrient infusion you ae considering adding in glutathione. Is it appropriate to mix glutathione into the IV solution an hour prior to starting the infusion? True False You are giving an infusion of alpha lipoic acid (ALA) Which of the following should you remember? ALA is given alone ALA dose is 100-250mg, max 600mg. ALA bags must be covered to decrease light exposure. All the above. Vitamin A can be mixed with other water soluble vitamins. True False PTC compounded for Mesotherapy can be added to an IV nutrient bag. True False Which of the following is TRUE of medical ozone. Medical ozone has 100% kill rate in the body Medical ozone is 50% ozone and 50% oxygen. Medical ozone is a strong antioxidant Medical ozone is 5% ozone and 95% oxygen. Ketamine is an NMDA receptor Agonist Antagonist Highest Bioavailable of ketamine is: IV IM Oral Topical Oral Ketamine Bioavailability is: 10% 20% 50% 80% Contraindications to Ketamine use are No psychosis No schizophrenia Uncontrolled hypertension All of the above Neuroinflammation can involve all the following EXCEPT? Peripheral nerves Central nervous system Present with pain and cognitive decline. Can cause increases in Testosterone, Estradiol and Progesterone levels. Neuroinflammatory calming strategies include all the following EXCEPT? Use of neurosteroids: Progesterone, Testosterone, DHEA Lowering histamine and aldehyde burden Taking ACE inhibitor blood pressure medications Low carbohydrate diets Insomnia has no impact on neuroinflammation and pain True False Which type of cannabinoid receptor is primarily found in the central nervous system? CB1 CB2 Both CB1 and CB2 Neither CB1 nor CB2 Which of the following is a possible function of CB2 receptors? Regulating mood and emotion Regulating appetite and metabolism Regulating immune function Regulating sleep-wake cycles Which of the following is a possible therapeutic use of CB2 receptor activation? Reducing anxiety and depression Relieving pain and inflammation Treating seizures and epilepsy Improving bone density and strength Which of the following best describes how CBD may help relieve pain? By blocking pain signals from reaching the brain By reducing inflammation in the body By increasing the body's production of endorphins By inducing a state of relaxation that reduces pain sensitivity Which of the following is an important consideration when using CBD to treat pain? CBD is not safe to use in combination with other pain medications CBD can cause addiction and dependence CBD can interact with other medications and cause side effects CBD does not require a prescription and can be used freely How does chronic pain affect the HPG axis? It decreases sex hormone production It increases sex hormone production It has no effect on sex hormone production Chronic pain affects sex hormone production only in males Which of the following is a potential consequence of opioid use on the HPG axis? Increased sex hormone production Decreased sex hormone production No effect on sex hormone production Opioid use affects sex hormone production only in females What does NAD stand for in the context of addiction treatment? Nicotine adenine dinucleotide Nicotinamide adenine dinucleotide Nicotinic acid dinucleotide Nicotinamide acid dinucleotide What is the primary function of NAD in the body? Producing energy in the mitochondria Regulating neurotransmitter levels in the brain Enhancing immune function All of the above How is NAD administered for addiction treatment? Intravenously Orally Topically Inhaled What is the primary goal of NAD therapy in addiction treatment? To eliminate cravings and withdrawal symptoms To induce a state of euphoria To increase dopamine levels in the brain To provide a placebo effect What is the theory behind the NAD+ addiction protocol? That addiction is caused by a deficiency of NAD+ in the brain That NAD+ can help repair damage to the brain caused by drug or alcohol abuse That NAD+ can help reduce withdrawal symptoms and cravings during detoxification All of the above Is NAD infusion a standalone treatment for addiction? Yes No What is the typical dose range with IV NAD+ for addiction? 100-500mg 2500 -10,000mg 500-1500mg 1000-2000mg LAMC is used to Support the electron transport chain to form Iron Supports the electron transport chain to form CoQ10 Supports the electron transport chain to form NADH Supports the electron transport chain to form ATP Palladium in LAMC is non-toxic and will not show up on heavy metal testing True False LAMC can be used for Neurological Support Autoimmunity Treatment for Radiation Damage All of the above LAMC which statement is true: Does not need to be given slow Can be put into an IV bag with other nutrients Can be given as a small, slow push Can be given as a push in large doses